Processing and application of arterial spin labeling magnetic resonance imaging
Type of documenthabilitační práce
Institutions assigning rankČeské vysoké učení technické v Praze. Fakulta elektrotechnická.
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This thesis focuses on the image processing methods for brain perfusion measurement using a magnetic resonance imaging (MRI) sequence called arterial spin labeling (ASL). We show the importance of dealing with brain volume changes as a measurement confounder, we propose a framework for integrating all processing steps in a robust processing pipeline, and lastly, we show an application of the ASL acquisition and processing to adverse effect measurements in healthy brain tissue of patients undergoing brain radio-chemotherapy demonstrating the usefulness of the method in uncovering structural and physiological changes in the brain.
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