Processing and application of arterial spin labeling magnetic resonance imaging
Type of document
habilitační prácehabilitation thesis
Author
Petr, Jan
Institutions assigning rank
České vysoké učení technické v Praze. Fakulta elektrotechnická.Metadata
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This thesis focuses on the image processing methods for brain perfusion measurement using
a magnetic resonance imaging (MRI) sequence called arterial spin labeling (ASL). We show
the importance of dealing with brain volume changes as a measurement confounder, we
propose a framework for integrating all processing steps in a robust processing pipeline, and
lastly, we show an application of the ASL acquisition and processing to adverse effect
measurements in healthy brain tissue of patients undergoing brain radio-chemotherapy
demonstrating the usefulness of the method in uncovering structural and physiological
changes in the brain.
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