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dc.contributor.authorTsegey T.
dc.contributor.authorKaushik S.
dc.contributor.authorBansal A.
dc.contributor.authorSlovak J.
dc.contributor.authorVojtisek L.
dc.date.accessioned2022-01-13T09:32:28Z
dc.date.available2022-01-13T09:32:28Z
dc.date.issued2021
dc.identifierV3S-354551
dc.identifier.citationTSEGEY, T., et al. Geodesic fiber tracking in white matter using activation function. Computer Methods and Programs in Biomedicine. 2021, Volume 208 ISSN 1872-7565. DOI 10.1016/j.cmpb.2021.106283.
dc.identifier.issn0169-2607 (print)
dc.identifier.issn1872-7565 (online)
dc.identifier.urihttp://hdl.handle.net/10467/99058
dc.description.abstractBackground and objective:The geodesic ray-tracing method has shown its effectiveness for the reconstruction of fibers in white matter structure. Based on reasonable metrics on the spaces of the diffusion tensors, it can provide multiple solutions and get robust to noise and curvatures of fibers. The choice of the metric on the spaces of diffusion tensors has a significant impact on the outcome of this method. Our objective is to suggest metrics and modifications of the algorithms leading to more satisfactory results in the construction of white matter tracts as geodesics. Methods:Starting with the DTI modality, we propose to rescale the initially chosen metric on the space of diffusion tensors to increase the geodetic cost in the isotropic regions. This change should be conformal in order to preserve the angles between crossing fibers. We also suggest to enhance the methods to be more robust to noise and to employ the fourth order tensor data in order to handle the fiber crossings properly. Results: We propose a way to choose the appropriate conformal class of metrics where the metric gets scaled according to tensor anisotropy. We use the logistic functions, which are commonly used in statistics as cumulative distribution functions. To prevent deviation of geodesics from the actual paths, we propose a hybrid ray-tracing approach. Furthermore, we suggest how to employ diagonal projections of 4th order tensors to perform fiber tracking in crossing regions.eng
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherElsevier Irland Ltd.
dc.relation.ispartofComputer Methods and Programs in Biomedicine
dc.subjectDiffusion Tensor Imagingeng
dc.subjectGeodesic equationseng
dc.subjectFibertrackingeng
dc.subjectactivation functioneng
dc.titleGeodesic fiber tracking in white matter using activation functioneng
dc.typečlánek v časopisecze
dc.typejournal articleeng
dc.identifier.doi10.1016/j.cmpb.2021.106283
dc.relation.projectidinfo:eu-repo/grantAgreement/EC/OPVVV/CZ.02.1.01%2F0.0%2F0.0%2F16_019%2F0000765/CZ/Research Center for Informatics/-
dc.rights.accessopenAccess
dc.type.statusPeer-reviewed
dc.type.versionpublishedVersion


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