• Distinct populations of neurons respond to emotional valence and arousal in the human subthalamic nucleus 

      Autor: Sieger T.; Serranová T.; Růžička F.; Vostatek P.; Wild J.; Šťastná D.; Bonnet C.; Novák D.; Růžička E.; Urgošík D.; Jech R.
      (Natl Acad Sciences, 2015)
      Both animal studies and studies using deep brain stimulation in humans have demonstrated the involvement of the subthalamic nucleus (STN) in motivational and emotional processes; however, participation of this nucleus in ...
    • External validation of extended prostate biopsy nomogram 

      Autor: Hrbáček J.; Minárik I.; Sieger T.; Babjuk M.
      (Polish Urological Association, 2015)
      Introduction Historical nomograms for the prediction of cancer on prostate biopsy, developed in the sex- tant biopsy era are no more accurate today. The aim of this study was an independent external validation of a 10-core ...
    • Eye Movements in Ephedrone-Induced Parkinsonism 

      Autor: Bonnet C.; Rusz J.; Megrelishvili M.; Sieger T.; Matoušková O.; Okujava M.; Brožová H.; Nikolai T.; Hanuška J.; Kapianidze M.; Mikeladze N.; Botchorishvili N.; Khatiashvili I.; Janelidze M.; Serranová T.; Fiala O.; Roth J.; Bergquist J.; Jech R.; Rivaud-Péchoux S.; Gaymard B.; Růžička E.
      (Public Library of Science, 2014)
      Patients with ephedrone parkinsonism (EP) show a complex, rapidly progressive, irreversible, and levodopa non-responsive parkinsonian and dystonic syndrome due to manganese intoxication. Eye movements may help to differentiate ...
    • Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State? 

      Autor: Hoskovcová M.; Dušek P.; Sieger T.; Brožová H.; Zárubová K.; Bezdíček O.; Šprdlík O.; Jech R.; Štochl J.; Roth J.; Růžička E.
      (Public Library of Science, 2015)
      Background Falls are a common complication of advancing Parkinson's disease (PD). Although numer- ous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study ...