• Articulatory undershoot of vowels in isolated REM sleep behavior disorder and early Parkinson's disease 

      Autor: Škrabal D.; Rusz J.; Novotný M.; Šonka K.; Růžička E.; Dušek P.; Tykalová T.
      (Nature Publishing Group, 2022)
      Imprecise vowels represent a common deficit associated with hypokinetic dysarthria resulting from a reduced articulatory range of motion in Parkinson's disease (PD). It is not yet unknown whether the vowel articulation ...
    • Automated video-based assessment of facial bradykinesia in de-novo Parkinson’s disease 

      Autor: Novotný M.; Tykalová T.; Růžičková H.; Růžička E.; Dušek P.; Rusz J.
      (Nature Publishing Group, 2022)
      Even though hypomimia is a hallmark of Parkinson’s disease (PD), objective and easily interpretable tools to capture the disruption of spontaneous and deliberate facial movements are lacking. This study aimed to develop a ...
    • A comparison of the directionality of head tremor between essential and dystonic tremor 

      Autor: Hubená T.; Hollý P.; Neťuková S.; Pavlíková A.; Růžička E.; Krupička R.
      (Elsevier, 2023)
      An essential tremor (ET) is the most common movement disorder in adults. In clinical practice, it is often difficult to distinguish between an essential tremor with head tremor, or dystonic head tremor (DT) in cervical ...
    • Cortical and subcortical morphometric changes and their relation to cognitive impairment in isolated REM sleep behavior disorder 

      Autor: Malá C.; Havlík F.; Mana J.; Nepožitek J.; Dostálová S.; Růžička E.; Šonka K.; Keller J.; Jech R.; Dušek P.; Bezdicek O.; Krupička R.
      (SPRINGER-VERLAG ITALIA SRL, 2023)
      Objective: To date, very few studies have focused on structural changes and their association with cognitive performance in isolated REM sleep behaviour disorder (iRBD). Moreover, the results of these studies are inconclusive. ...
    • Distinct populations of neurons respond to emotional valence and arousal in the human subthalamic nucleus 

      Autor: Sieger T.; Serranová T.; Růžička F.; Vostatek P.; Wild J.; Šťastná D.; Bonnet C.; Novák D.; Růžička E.; Urgošík D.; Jech R.
      (Natl Acad Sciences, 2015)
      Both animal studies and studies using deep brain stimulation in humans have demonstrated the involvement of the subthalamic nucleus (STN) in motivational and emotional processes; however, participation of this nucleus in ...
    • The effects of accelerometer sensor position on freezing gait ratio parameters 

      Autor: Neťuková S.; Horáková L.; Hubená T.; Růžička E.; Szabó Z.; Krupička R.
      (Elsevier, 2023)
      Freezing of gait (FoG) is an episodic gait pattern characterised by the inability to step that occurs on initiation or turning while walking for those with Parkinson’s disease (PD). This phenomenon is one of the most ...
    • Essential and dystonic head tremor: More similarities than differences 

      Autor: Hollý P.; Hubená T.; Kemlink D.; Ulmanová O.; Rusz J.; Krupička R.; Jech R.; Růžička E.
      (Elsevier Science, 2023)
      Introduction: Head tremor is a common symptom of essential tremor (ET) and cervical dystonia (CD). In clinical practice, it is often difficult to distinguish between these two conditions, especially in cases where head ...
    • Eye Movements in Ephedrone-Induced Parkinsonism 

      Autor: Bonnet C.; Rusz J.; Megrelishvili M.; Sieger T.; Matoušková O.; Okujava M.; Brožová H.; Nikolai T.; Hanuška J.; Kapianidze M.; Mikeladze N.; Botchorishvili N.; Khatiashvili I.; Janelidze M.; Serranová T.; Fiala O.; Roth J.; Bergquist J.; Jech R.; Rivaud-Péchoux S.; Gaymard B.; Růžička E.
      (Public Library of Science, 2014)
      Patients with ephedrone parkinsonism (EP) show a complex, rapidly progressive, irreversible, and levodopa non-responsive parkinsonian and dystonic syndrome due to manganese intoxication. Eye movements may help to differentiate ...
    • Linguistic Abnormalities in Isolated Rapid Eye Movement Sleep Behavior Disorder 

      Autor: Šubert M.; Šimek M.; Novotný M.; Tykalová T.; Bezdíček O.; Růžička E.; Šonka K.; Dušek P.; Rusz J.
      (Wiley-Liss, 2022)
      Background: Patients with synucleinopathies frequently display language abnormalities. However, whether patients with isolated rapid eye movement sleep behavior disorder (iRBD) have prodromal language impairment remains ...
    • Long-Term Averaged Spectrum Descriptors of Dysarthria in Patients With Parkinson’s Disease Treated With Subthalamic Nucleus Deep Brain Stimulation 

      Autor: Švihlík J.; Novotný M.; Tykalová T.; Poláková K.; Brožová H.; Krýže P.; Sousa M.; Krack P.; Tripoliti E.; Růžička E.; Jech R.; Rusz J.
      (AMER SPEECH-LANGUAGE-HEARING ASSOC, 2022)
      Purpose: This study aimed to evaluate whether long-term averaged spectrum (LTAS) descriptors for reading and monologue are suitable to detect worsening of dysarthria in patients with Parkinson’s disease (PD) treated with ...
    • Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State? 

      Autor: Hoskovcová M.; Dušek P.; Sieger T.; Brožová H.; Zárubová K.; Bezdíček O.; Šprdlík O.; Jech R.; Štochl J.; Roth J.; Růžička E.
      (Public Library of Science, 2015)
      Background Falls are a common complication of advancing Parkinson's disease (PD). Although numer- ous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study ...
    • Spatial and temporal characteristics of gait as outcome measures in multiple sclerosis (EDSS 0 to 6.5) 

      Autor: Lizrova Preiningerova J.; Novotná K.; Rusz J.; Suchá L.; Růžička E.; Havrdová E.
      (BioMed Central, 2015)
      Background: Gait impairment represents one of the most common and disabling symptom of multiple sclerosis. Quantification of the gait is an important aspect of clinical trials. In order to identify which temporal or spatial ...
    • Speech and gait abnormalities in motor subtypes of de-novo Parkinson's disease 

      Autor: Rusz J.; Krupička R.; Neťuková S.; Tykalová T.; Novotný M.; Novák J.; Dušek P.; Růžička E.
      (John Wiley & Sons, 2023)
      AimTo investigate the presence and relationship of temporal speech and gait parameters in patients with postural instability/gait disorder (PIGD) and tremor-dominant (TD) motor subtypes of Parkinson's disease (PD). ...
    • Spoken Language Alterations can Predict Phenoconversion in Isolated rapid eye movement Sleep Behavior Disorder: A Multicentric Study 

      Autor: Šubert M.; Novotný M.; Tykalová T.; Hlavnička J.; Dušek P.; Růžička E.; Škrabal D.; Pelletier A.; Postuma R.B.; Montplaisir J.; Gagnon J.-F.; Galbiati A.; Ferini-Strambi L.; Marelli S.; St Louis E.K.; Timm P.C.; Teigen L.N.; Janzen A.; Oertel W.; Heim B.; Holzknecht E.; Stefani A.; Högl B.; Dauvilliers Y.; Evangelista E.; Šonka K.; Rusz J.
      (John Wiley & Sons, 2024)
      Objective: This study assessed the relationship between speech and language impairment and outcome in a multicenter cohort of isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD).Methods: Patients ...
    • The effects of cognitive impairment on gait in Parkinson's disease 

      Autor: Krupička R.; Malá C.; Neťuková S.; Hubená T.; Vážná A.; Novák J.; Růžička E.; Bezdíček O.
      (Elsevier, 2023)
      Introduction: Gait and cognitive deficits are common symptoms of Parkinson's disease (PD). Cognitive deficits can manifest themselves in gait impairment and are tested with the gait-cognitive dual task (DT). Although a ...