Ligands in macromolecular structures are used as tools to decipher the
structure:function relationship of the target molecules. They proved to be useful in design
of novel inhibitors of glutaminyl cyclases, inhibitors of bovine cationic trypsin, inhibitors
of biotechnologic nucleases, and overall understanding of human interferon γ receptor 2.
en
dc.language.iso
čeština
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dc.publisher
ČVUT. Fakulta jaderná a fyzikálně inženýrská.
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dc.subject
protein
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dc.subject
ligand
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dc.subject
X-ray structure analysis
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dc.title
Pozorovaní interakcí bílkovin s ligandy pomocí makromolekulární rentgenové krystalografie