Abstract
The completed IceCube Observatory, the first km3 neutrino telescope, is already providing the most stringent limits on the flux of high energy cosmic neutrinos from point-like and diffuse galactic and extra-galactic sources. The non-detection of extra-terrestrial neutrinos has important consequences on the origin of the cosmic rays. Here the current status of astrophysical neutrino searches, and of the observation of a persistent cosmic ray anisotropy above 100TeV, are reviewed.