DEPENDENCE OF THE VISCOSITY COEFFICIENT OF THE NIOSOMAL DISPERSION ON THE TEMPERATURE AND PARTICLE SIZE OF THE DISPERSED PHASE

Abstract

The aim of this study was to experimentally investigate the dependence of viscosity coefficient of niosomal dispersion based on PEG-12 Dimethicone on the temperature and size of niosomes vesicles. The experiments were carried out with niosomes, the average size of which varied from 85 to 125 nm. The temperature varied from 20 to 60 °C, the volume concentration varied from 1 to 10 %. The particle size was determined by scanning electron microscopy (SEM) with subsequent statistical data processing. This study showed that the viscosity of niosomal dispersions significantly depends on both the temperature and the size of niosomes vesicles. With increasing temperature, the viscosity of niosomal dispersions decreases and with increasing particle size, the viscosity increases.