Psilobeats: Lokalizace efektů psilocybinu na lidský mozek ve vztahu k vnímání hudby

Abstract

As a part of a study into psilocybin's effect on the human brain, the Czech National Institute of Mental Health (NIMH) conducted a series of tests of psilocybin's influence on music perception. This thesis attempts to find a way to locate changes in the brain and obtain quantifiable and intelligible information about the scale of psilocybin's influence on perceiving different aspects of music from the provided data. Two methods aiming to obtain these results were proposed and tested. The first method is finding coherence between signals using the DICS method. It should lead to obtaining both information about which aspects of music are perceived differently when under the influence and the location of the parts of the brain that are affected. The second method is based on correlating features from EEG and the cepstrum of music. In contrast to DICS analysis, cepstral analysis is less spatially specific in the EEG domain, but it is more sensitive in capturing and describing the underlying structure of the music.As a part of a study into psilocybin's effect on the human brain, the Czech National Institute of Mental Health (NIMH) conducted a series of tests of psilocybin's influence on music perception. This thesis attempts to find a way to locate changes in the brain and obtain quantifiable and intelligible information about the scale of psilocybin's influence on perceiving different aspects of music from the provided data. Two methods aiming to obtain these results were proposed and tested. The first method is finding coherence between signals using the DICS method. It should lead to obtaining both information about which aspects of music are perceived differently when under the influence and the location of the parts of the brain that are affected. The second method is based on correlating features from EEG and the cepstrum of music. In contrast to DICS analysis, cepstral analysis is less spatially specific in the EEG domain, but it is more sensitive in capturing and describing the underlying structure of the music.