Vytvoření nástroje pro přenos expertní analýzy cytometrických dat do open source prostředí pro zlepšení lékařské diagnostiky leukemií a jiných onemocnění
Development of a tool for transfer of expert analysis of cytometric data to an open source environment to improve the medical diagnosis of leukemias and other diseases
Type of document
bakalářská prácebachelor thesis
Author
Michaela Součková
Supervisor
Dvorský Bohuslav
Opponent
Staněk David
Field of study
Biomedicínská informatikaStudy program
Biomedicínská a klinická technikaInstitutions assigning rank
katedra biomedicínské informatikyRights
A university thesis is a work protected by the Copyright Act. Extracts, copies and transcripts of the thesis are allowed for personal use only and at one?s own expense. The use of thesis should be in compliance with the Copyright Act http://www.mkcr.cz/assets/autorske-pravo/01-3982006.pdf and the citation ethics http://knihovny.cvut.cz/vychova/vskp.htmlVysokoškolská závěrečná práce je dílo chráněné autorským zákonem. Je možné pořizovat z něj na své náklady a pro svoji osobní potřebu výpisy, opisy a rozmnoženiny. Jeho využití musí být v souladu s autorským zákonem http://www.mkcr.cz/assets/autorske-pravo/01-3982006.pdf a citační etikou http://knihovny.cvut.cz/vychova/vskp.html
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The aim is to parse FlowJo (v 10.5.3) workspace file in R language to extract stored specifics of flow cytometry data analysis and subsequently transform and process the raw data stored separately in a file of FCS format. If both done correctly we get both, equivalently transformed data and indices of datapoints corresponding to expertly defined datapoints (cell populations) as "gated" by FlowJo user. This is necessary for combination and comparison of expert manual analysis and computational approaches. The aim is to parse FlowJo (v 10.5.3) workspace file in R language to extract stored specifics of flow cytometry data analysis and subsequently transform and process the raw data stored separately in a file of FCS format. If both done correctly we get both, equivalently transformed data and indices of datapoints corresponding to expertly defined datapoints (cell populations) as "gated" by FlowJo user. This is necessary for combination and comparison of expert manual analysis and computational approaches.