ŠIMEK, M., et al. Comparison of acoustic measures of dysphonia in Parkinson's disease and Huntington's disease: Effect of sex and speaking task. In: Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH 2023. Interspeech, Dublin, 2023-08-21/2023-08-24. Bochum: ISCA - International Speech Communication Association, 2023. p. 2398-2402. ISSN 2308-457X. DOI 10.21437/Interspeech.2023-1915.
This study investigated whether voice quality is differentially affected in two distinct basal ganglia disorders causing hypokinetic and hyperkinetic dysarthria, including effects of gender and speaking task. The sustained vowel phonations and monologues of 40 de novo Parkinson's disease (PD) patients, 40 Huntington's disease (HD) patients, and 40 healthy control participants were evaluated. Using cepstral peak prominence extracted from sustained phonation, differences from controls were found for male and female HD patients (p < 0.05) but only male PD patients (p < 0.05). Using the glottal-to-noise excitation ratio obtained from monologue, differences from controls were detected for male and female PD groups (p < 0.05) but only male HD group (p < 0.05). In general, female patients show better voice quality. Our findings highlight that selecting suitable acoustic measures and speaking material is essential for adequate evaluation of dysphonia severity across differing etiologies.
eng
dc.format.mimetype
application/pdf
dc.language.iso
eng
dc.publisher
ISCA - International Speech Communication Association
dc.relation.ispartof
Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH 2023
dc.subject
Basal ganglia
eng
dc.subject
Huntington's disease
eng
dc.subject
Parkinson's disease
eng
dc.subject
pathological voice
eng
dc.title
Comparison of acoustic measures of dysphonia in Parkinson's disease and Huntington's disease: Effect of sex and speaking task
info:eu-repo/grantAgreement/Ministry of Health/NU/NU20-08-00445/CZ/Smart Speech Biomarkers for Parkinson’s Disease and Other Synucleinopathies/SMARTSPEECH
dc.relation.projectid
info:eu-repo/grantAgreement/Ministry of Education, Youth and Sports/LX/LX22NPO5107/CZ/National institute for Neurological Research/NPO-NEURO-D