Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology
Type of document
článek v časopisejournal article
Peer-reviewed
publishedVersion
Author
Sahylí Ortega Pijeira M.
Viltres H.
Kozempel J.
Sakmár M.
Vlk M.
İlem‑Özdemir D.
Ekinci M.
Srinivasan S.
Rajabzadeh A.R.
Ricci‑Junior E.
Magalhães Rebelo Alencar L.
Al Qahtani M.
Santos‑Oliveira R.
Rights
Creative Commons Attribution (CC BY) 4.0http://creativecommons.org/licenses/by/4.0/
openAccess
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Show full item recordAbstract
Background: Recent advances in nanotechnology have ofered new hope for cancer
detection, prevention, and treatment. Nanomedicine, a term for the application of
nanotechnology in medical and health felds, uses nanoparticles for several applica‑
tions such as imaging, diagnostic, targeted cancer therapy, drug and gene delivery,
tissue engineering, and theranostics.
Results: Here, we overview the current state-of-the-art of radiolabeled nanoparticles
for molecular imaging and radionuclide therapy. Nanostructured radiopharmaceuticals
of technetium-99m, copper-64, lutetium-177, and radium-223 are discussed within the
scope of this review article.
Conclusion: Nanoradiopharmaceuticals may lead to better development of thera‑
nostics inspired by ingenious delivery and imaging systems. Cancer nano-theranos‑
tics have the potential to lead the way to more specifc and individualized cancer
treatment.
Keywords: Radiolabeled nanoparticles, Technetium-99m, Copper-64, Lutetium-177,
Radium-223, Molecular imaging, Radionuclide therapy, Theranostics, Toxicity,
Radiopharmacy
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Except where otherwise noted, this item's license is described as Creative Commons Attribution (CC BY) 4.0