High Frequency Oscillations analysis in scalp EEG in Focal Cortical Dysplasia patients.
Analýza vysokofrekvenčních oscilací ve skalpovém EEG pacientů s fokální kortikální dysplázií
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České vysoké učení technické v Praze
Czech Technical University in Prague
Czech Technical University in Prague
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High Frequency Oscillations (HFO) is currently a promising biomarker for epileptogenicity. The research and assessment to properly define and describe its characteristics is still ongoing. In this thesis the state of the art regarding the HFO is presented and the HDEEG scalp recordings of Focal Cortical Dysplasia (FCD) patients being treated at FN Motol Hospital is evaluated. The HFO occurring simultaneously with Interictal Epileptiform discharges (IED) are analyzed with the help of signal visualization tools in the time and the time-frequency domains, and an attempt to connect FCD types to detected HFOs took place. In addition, the comparison of the HFO-based visual analysis and MELD results is performed. Keywords: HFO, HDEEG, scalp EEG, epilepsy, FCD, signal processing
High Frequency Oscillations (HFO) is currently a promising biomarker for epileptogenicity. The research and assessment to properly define and describe its characteristics is still ongoing. In this thesis the state of the art regarding the HFO is presented and the HDEEG scalp recordings of Focal Cortical Dysplasia (FCD) patients being treated at FN Motol Hospital is evaluated. The HFO occurring simultaneously with Interictal Epileptiform discharges (IED) are analyzed with the help of signal visualization tools in the time and the time-frequency domains, and an attempt to connect FCD types to detected HFOs took place. In addition, the comparison of the HFO-based visual analysis and MELD results is performed.
High Frequency Oscillations (HFO) is currently a promising biomarker for epileptogenicity. The research and assessment to properly define and describe its characteristics is still ongoing. In this thesis the state of the art regarding the HFO is presented and the HDEEG scalp recordings of Focal Cortical Dysplasia (FCD) patients being treated at FN Motol Hospital is evaluated. The HFO occurring simultaneously with Interictal Epileptiform discharges (IED) are analyzed with the help of signal visualization tools in the time and the time-frequency domains, and an attempt to connect FCD types to detected HFOs took place. In addition, the comparison of the HFO-based visual analysis and MELD results is performed.